كتاب  Aspirinكتب الطب

كتاب Aspirin

Aspirin من كتب طب بيطرى Draft copy for review purposes only. Private property of USPC, Inc. Not for public disclosure. All rights reserved 1 Note: This is a revised monograph. Underscored information indicates material proposed for addition; strikethroughs indicate material proposed for deletion. ASPIRIN Veterinary—Systemic Some commonly used brand names are: For veterinary-labeled products— Advanced Care; AniPrin EZ; AniPrin F; AniPrin LG PM; AniPrin P; Arthricare; Arthri-Eze; Asen P ; Asen 240 Bolus; Asp - Rin; Centra ASA 240 ‡; Durasol; Aspir-Eze; Aspir-Flex; Equi-Phar ArthriBan; Equi - Prin; Equi- Spirin; Health Measures; Palaprin 65; Palaprin 325; and Vetrin. For human-labeled products— Apo-ASA ‡ ; Asaphen; Asaphen Orange; Aspirin Caplets; Aspirin Childre n’s Tablets; Aspirin Tablets; Aspir - Low; Aspirtab; Aspirtab - Max; Bayer Children’s Aspirin; Empirin; Entrophen 10; Entrophen Extra Strength; Extra Strength Bayer Aspirin Caplets; Extra Strength Bayer Aspirin Tablets; Genuine Bayer Aspirin Caplets; Genuine Bayer Aspirin Tablets; Halfprin; Headache Tablet; Healthprin Adult Low Strength; Healthprin Full Strength; Healthprin Half - Dose; Norwich Aspirin; Novasen; PMS - ASA; and St. Joseph Adult Chewable Aspirin . Note: For a listing of dosage forms and brand names by country availability, see the Dosage Forms section(s). ‡ Aspirin is a brand name in Canada; acet ylsalicylic acid is the generic name. ASA, a commonly used designation for aspirin (or acetylsalicylic acid) in both the U.S. and Canada, is the term used in Canadian product labeling. Category: Analgesic, anti-inflammatory (nonsteroidal); antidiarrheal ( Escherichia coli –induced diarrhea); antipyretic; antirheumatic (nonsteroidal anti-inflammatory); platelet aggregation inhibitor. Indications Note: The text between EL US and EL describes uses that are not included in U.S. product labeling. Text between EL CAN and EL describes uses that are not included in Canadian product labeling. The EL US or EL CAN designation can signify a lack of product availability in the country indicated. See the Dosage Forms section of this monograph to confirm availability. Accepted Note: Although veterinary forms of aspirin are marketed with label indications for pain, fever, and inflammation , the drug has never been approved by the United States Food and Drug Administration Center for Veterinary Medicine (FDA CVM) for these purposes. EL CAN Inflammation (treatment) EL — Dogs and EL US cats EL : Aspirin is used for the relief of inflammation associated with arthritis and joint problems. {R-39} Pain (treatment)— Cattle, EL CAN dogs , pigs EL , and EL US,CAN cats EL : Aspirin is used for relief from mild to modera te somatic pain, such as incisional pain following surgery, pain following dental procedures, and discomfort associated with cystitis. {R-39-41} EL CAN Fever (treatment) EL — Cattle, dogs, pigs, and EL US cats EL : Aspirin is used to reduce fever; however, the tr eatment of fever with antipyretic medications is controversial and specific therapy for the underlying disease should be sought. {R-39; 41} Acceptance not established Potentially effective Inflammation (treatment); Pain (treatment); or EL CAN Fever (treatment) EL — Horses: Due to the rapi d elimination of salicylate by horses, it is ques tionable whether therapeutic yet nontoxic concentrations can be maintained in the horse using conventional dosage intervals. EL US,CAN Cardiomyopathy (treatment adjunct) EL — Cats: Thromboembolism Regulatory Considerations U.S.— Aspirin does not have specific approval by the Food and Drug Administration for use in animals; therefore, there are no established withdrawal times for use of this medication in foodproducing animals.{R-13} See recommendations on withdrawals for extra-label administration in the Dosage Forms section of this monograph. Chemistry Source: Manufactured from salicylic acid and acetic anhydride.{R-14} Chemical name: Benzoic acid, 2-(acetyloxy)-.{R-15} Molecular formula: C9H8O4.{R-15} Molecular weight: 180.16.{R-15} Description: Aspirin USP—White crystals, commonly tabular or needlelike, or white, crystalline powder. Is odorless or has a faint odor. Is stable in dry air; in moist air it gradually hydrolyzes to salicylic and acetic acids.{R-16} pKa: 3.5.{R-14; 17} Solubility: Aspirin USP—Slightly soluble in water; freely soluble in alcohol; soluble in chloroform and in ether; sparingly soluble in absolute ether.{R-16} Pharmacology/Pharmacokinetics Note: See also Table 1. Pharmacology/Pharmacokinetics at the end of this monograph. Mechanism of action/Effect: The effectiveness of aspirin is largely due Draft copy for review purposes only. Private property of USPC, Inc. Not for public disclosure. All rights reserved 3 to its ability to inhibit prostaglandin synthesis. This is done by irreversibly blocking cyclooxygenase (prostaglandin synthase), which catalyzes the conversion of arachidonic acid to endoperoxide compounds; at appropriate doses, the drug decreases the formation of both the prostaglandins and thromboxane A2 but not the leukotrienes.{R-18} Other actions/effects: It has been proposed that the gastrointestinal toxicity of salicylates, especially aspirin, may be caused primarily by reduction of the activity of prostaglandins (which exert a protective effect on the gastrointestinal mucosa) because upper gastrointestinal toxicity has been reported following rectal or parenteral administration of a nonsteroidal anti-inflammatory drug. However, when administered orally, these acidic medications (unless administered in an enteric-coated formulation) probably also exert a direct irritant or erosive effect on the mucosa.{R-19} Absorption: Salicylates are rapidly and completely absorbed following oral administration to cats, dogs, and pigs. They are slowly and incompletely absorbed by ruminants and horses. Distribution: Free aspirin is widely distributed into various tissues of the body. Biotransformation: Aspirin is rapidly hydrolyzed to salicylic acid by plasma esterases in all species.{R-20} Time to peak plasma concentration: Human data—Generally 1 to 2 hours with single doses; may be more rapid with liquid dosage forms; may be delayed with delayed-release tablet or capsule formulations.{R- 19} Peak plasma concentration: Therapeutic serum salicylate concentrations varied from 9.15 to 11.90 mg/dL in dogs given plain aspirin orally at a dose of 25 mg per kg of body weight (mg/kg) every 8 hours.{R-21} Milk concentrations: Human data—Peak salicylate concentrations of 173 to 483 mcg/mL were measured in breast milk 5 to 8 hours after maternal ingestion of a single total aspirin dose of 650 mg.{R-19} Elimination: Renal, primarily as free salicylic acid and as conjugated metabolites. In the horse, salicylic acid is the primary salicyl compound found in urine while in other domesticated species varying quantities of metabolites are excreted. Cats: Aspirin has been shown to have dose-dependent elimination in cats, with longer elimination half-lives seen with larger doses. Precautions to Consider Species sensitivity Cats—Cats may develop salicylism unless aspirin dosage is carefully controlled. Cats are deficient in the enzyme glucuronyl transferase, an important conjugation mechanism in other species. Dogs—Some individual dogs will not tolerate continuous therapy with aspirin because they develop gastrointestinal irritation. Lactation Salicylates are distributed into milk; however, problems have not been observed in nursing offspring. Pediatrics Salicylates are more slowly eliminated in animals less than 30 days of age. In addition, the extent of protein binding is less during this period. Human precautions to consider{R-19} In addition to the above precautions for the use of this medication in animals, the
-
من كتب الطب - مكتبة كتب الطب.

وصف الكتاب : Aspirin من كتب طب بيطرى

Draft copy for review purposes only. Private property of USPC,
Inc. Not for public disclosure.
All rights reserved
1
Note: This is a
revised
monograph. Underscored
information indicates material proposed for addition;
strikethroughs
indicate material proposed for deletion.
ASPIRIN
Veterinary—Systemic
Some commonly used
brand names
are:
For veterinary-labeled products—
Advanced Care;
AniPrin EZ;
AniPrin
F; AniPrin LG PM;
AniPrin P; Arthricare;
Arthri-Eze;
Asen P
;
Asen 240 Bolus;
Asp
-
Rin;
Centra ASA 240
‡;
Durasol;
Aspir-Eze; Aspir-Flex;
Equi-Phar ArthriBan; Equi
-
Prin;
Equi-
Spirin; Health Measures;
Palaprin 65;
Palaprin 325;
and
Vetrin.
For human-labeled products—
Apo-ASA

;
Asaphen; Asaphen Orange;
Aspirin Caplets; Aspirin Childre
n’s Tablets; Aspirin Tablets;
Aspir
-
Low; Aspirtab; Aspirtab
-
Max;
Bayer Children’s Aspirin;
Empirin;
Entrophen 10; Entrophen Extra Strength;
Extra
Strength Bayer Aspirin Caplets;
Extra Strength Bayer Aspirin
Tablets; Genuine Bayer Aspirin
Caplets; Genuine Bayer Aspirin
Tablets; Halfprin;
Headache Tablet; Healthprin Adult Low
Strength; Healthprin Full Strength; Healthprin Half
-
Dose;
Norwich Aspirin; Novasen;
PMS
-
ASA;
and
St. Joseph Adult
Chewable Aspirin
.
Note: For a listing of dosage forms and brand names by country
availability, see the
Dosage Forms
section(s).

Aspirin
is a brand name in Canada; acet
ylsalicylic acid is the generic
name. ASA, a commonly used designation for aspirin (or acetylsalicylic
acid) in both the U.S. and Canada, is
the term used in Canadian product
labeling.
Category:
Analgesic, anti-inflammatory
(nonsteroidal); antidiarrheal
(
Escherichia coli
–induced diarrhea); antipyretic; antirheumatic
(nonsteroidal anti-inflammatory);
platelet aggregation inhibitor.
Indications
Note: The text between
EL
US
and
EL
describes uses that are not included in
U.S. product labeling. Text between
EL
CAN
and
EL
describes uses that
are not included in Canadian product labeling.
The
EL
US
or
EL
CAN
designation can signify a lack of product availability
in the country indicated. See the
Dosage Forms
section of this
monograph to confirm availability.
Accepted
Note: Although veterinary forms of
aspirin are marketed with label
indications for
pain, fever,
and
inflammation
, the drug has never
been approved by the United States Food and Drug Administration
Center for Veterinary Medicine
(FDA CVM) for these purposes.
EL
CAN
Inflammation (treatment)
EL

Dogs
and
EL
US
cats
EL
: Aspirin is used for
the relief of inflammation associated
with arthritis and joint problems.
{R-39}
Pain (treatment)—
Cattle,
EL
CAN
dogs
,
pigs
EL
, and
EL
US,CAN
cats
EL
: Aspirin is
used for relief from mild to modera
te somatic pain, such as incisional
pain following surgery, pain following dental procedures, and
discomfort associated with cystitis.
{R-39-41}
EL
CAN
Fever (treatment)
EL

Cattle, dogs, pigs,
and
EL
US
cats
EL
: Aspirin is
used to reduce fever; however, the tr
eatment of fever with antipyretic
medications is controversial and
specific therapy for the underlying
disease should be sought.
{R-39; 41}
Acceptance not established
Potentially effective
Inflammation (treatment);
Pain (treatment); or
EL
CAN
Fever (treatment)
EL

Horses:
Due to the rapi
d elimination of
salicylate by horses, it is ques
tionable whether therapeutic yet
nontoxic concentrations can be maintained in the horse using
conventional dosage intervals.
EL
US,CAN
Cardiomyopathy (treatment adjunct)
EL

Cats:
Thromboembolism

Regulatory Considerations
U.S.—
Aspirin does not have specific approval by the Food and Drug
Administration for use in animals; therefore, there are no
established withdrawal times for use of this medication in foodproducing
animals.{R-13} See recommendations on withdrawals for
extra-label administration in the Dosage Forms section of this
monograph.
Chemistry
Source: Manufactured from salicylic acid and acetic anhydride.{R-14}
Chemical name: Benzoic acid, 2-(acetyloxy)-.{R-15}
Molecular formula: C9H8O4.{R-15}
Molecular weight: 180.16.{R-15}
Description: Aspirin USP—White crystals, commonly tabular or needlelike,
or white, crystalline powder. Is odorless or has a faint odor. Is
stable in dry air; in moist air it gradually hydrolyzes to salicylic and
acetic acids.{R-16}
pKa: 3.5.{R-14; 17}
Solubility: Aspirin USP—Slightly soluble in water; freely soluble in
alcohol; soluble in chloroform and in ether; sparingly soluble in
absolute ether.{R-16}
Pharmacology/Pharmacokinetics
Note: See also Table 1. Pharmacology/Pharmacokinetics at the end of
this monograph.
Mechanism of action/Effect: The effectiveness of aspirin is largely due
Draft copy for review purposes only. Private property of USPC, Inc. Not for public disclosure. All rights reserved 3
to its ability to inhibit prostaglandin synthesis. This is done by
irreversibly blocking cyclooxygenase (prostaglandin synthase),
which catalyzes the conversion of arachidonic acid to endoperoxide
compounds; at appropriate doses, the drug decreases the formation
of both the prostaglandins and thromboxane A2 but not the
leukotrienes.{R-18}
Other actions/effects: It has been proposed that the gastrointestinal
toxicity of salicylates, especially aspirin, may be caused primarily
by reduction of the activity of prostaglandins (which exert a
protective effect on the gastrointestinal mucosa) because upper
gastrointestinal toxicity has been reported following rectal or
parenteral administration of a nonsteroidal anti-inflammatory drug.
However, when administered orally, these acidic medications
(unless administered in an enteric-coated formulation) probably also
exert a direct irritant or erosive effect on the mucosa.{R-19}
Absorption: Salicylates are rapidly and completely absorbed following
oral administration to cats, dogs, and pigs. They are slowly and
incompletely absorbed by ruminants and horses.
Distribution: Free aspirin is widely distributed into various tissues of the
body.
Biotransformation: Aspirin is rapidly hydrolyzed to salicylic acid by
plasma esterases in all species.{R-20}
Time to peak plasma concentration: Human data—Generally 1 to 2
hours with single doses; may be more rapid with liquid dosage forms;
may be delayed with delayed-release tablet or capsule formulations.{R-
19}
Peak plasma concentration: Therapeutic serum salicylate
concentrations varied from 9.15 to 11.90 mg/dL in dogs given plain
aspirin orally at a dose of 25 mg per kg of body weight (mg/kg) every
8 hours.{R-21}
Milk concentrations: Human data—Peak salicylate concentrations of
173 to 483 mcg/mL were measured in breast milk 5 to 8 hours after
maternal ingestion of a single total aspirin dose of 650 mg.{R-19}
Elimination: Renal, primarily as free salicylic acid and as conjugated
metabolites. In the horse, salicylic acid is the primary salicyl
compound found in urine while in other domesticated species varying
quantities of metabolites are excreted.
Cats: Aspirin has been shown to have dose-dependent elimination in
cats, with longer elimination half-lives seen with larger doses.
Precautions to Consider
Species sensitivity
Cats—Cats may develop salicylism unless aspirin dosage is carefully
controlled. Cats are deficient in the enzyme glucuronyl transferase, an
important conjugation mechanism in other species.
Dogs—Some individual dogs will not tolerate continuous therapy with
aspirin because they develop gastrointestinal irritation.
Lactation
Salicylates are distributed into milk; however, problems have not been
observed in nursing offspring.
Pediatrics
Salicylates are more slowly eliminated in animals less than 30 days of
age. In addition, the extent of protein binding is less during this
period.
Human precautions to consider{R-19}
In addition to the above precautions for the use of this medication in
animals, the

عدد مرات التحميل : 11644 مرّة / مرات.
تم اضافته في : السبت , 26 مارس 2016م.
حجم الكتاب عند التحميل : 121.3 كيلوبايت .

ولتسجيل ملاحظاتك ورأيك حول الكتاب يمكنك المشاركه في التعليقات من هنا:

Aspirin من كتب طب بيطرى


Draft copy for review purposes only.  Private property of USPC, 
Inc.  Not for public disclosure.                 
All rights reserved
1
Note: This is a 
revised
 monograph. Underscored
 information indicates material proposed for addition; 
strikethroughs
 indicate material proposed for deletion.  
ASPIRIN 
Veterinary—Systemic 
Some commonly used 
brand names 
are: 
For veterinary-labeled products—
Advanced Care; 
AniPrin EZ; 
AniPrin 
F; AniPrin LG PM; 
AniPrin P; Arthricare; 
Arthri-Eze; 
Asen P
;
Asen 240 Bolus;
Asp
-
Rin; 
Centra ASA 240
‡;
 Durasol; 
Aspir-Eze; Aspir-Flex; 
Equi-Phar ArthriBan; Equi
-
Prin; 
Equi-
Spirin; Health Measures; 
Palaprin 65; 
Palaprin 325; 
and 
Vetrin.
For human-labeled products—
Apo-ASA

;
 Asaphen; Asaphen Orange; 
Aspirin Caplets; Aspirin Childre
n’s Tablets; Aspirin Tablets; 
Aspir
-
Low; Aspirtab; Aspirtab
-
Max; 
Bayer Children’s Aspirin; 
Empirin; 
Entrophen 10; Entrophen Extra Strength; 
Extra 
Strength Bayer Aspirin Caplets;
 Extra Strength Bayer Aspirin 
Tablets; Genuine Bayer Aspirin 
Caplets; Genuine Bayer Aspirin 
Tablets; Halfprin; 
Headache Tablet; Healthprin Adult Low 
Strength; Healthprin Full Strength; Healthprin Half
-
Dose; 
Norwich Aspirin; Novasen; 
PMS
-
ASA;
and 
St. Joseph Adult 
Chewable Aspirin

Note: For a listing of dosage forms and brand names by country 
availability, see the 
Dosage Forms 
section(s). 

Aspirin 
is a brand name in Canada; acet
ylsalicylic acid is the generic 
name. ASA, a commonly used designation for aspirin (or acetylsalicylic 
acid) in both the U.S. and Canada, is
 the term used in Canadian product 
labeling. 
Category: 
Analgesic, anti-inflammatory 
(nonsteroidal); antidiarrheal 
(
Escherichia coli
–induced diarrhea); antipyretic; antirheumatic 
(nonsteroidal anti-inflammatory); 
platelet aggregation inhibitor. 
Indications 
Note: The text between 
EL
US 
and
EL
 describes uses that are not included in 
U.S. product labeling. Text between 
EL
CAN 
and
EL
 describes uses that 
are not included in Canadian product labeling. 
The 
EL
US
or 
EL
CAN
 designation can signify a lack of product availability 
in the country indicated. See the 
Dosage Forms
 section of this 
monograph to confirm availability. 
Accepted 
Note: Although veterinary forms of 
aspirin are marketed with label 
indications for 
pain, fever, 
and 
inflammation
, the drug has never 
been approved by the United States Food and Drug Administration 
Center for Veterinary Medicine
 (FDA CVM) for these purposes.
EL
CAN
Inflammation (treatment)
EL

Dogs
 and 
EL
US
cats
EL
: Aspirin is used for 
the relief of inflammation associated 
with arthritis and joint problems. 
{R-39}
Pain (treatment)—
Cattle,
EL
CAN
dogs

pigs
EL
, and 
EL
US,CAN
cats
EL
: Aspirin is 
used for relief from mild to modera
te somatic pain, such as incisional 
pain following surgery, pain following dental procedures, and 
discomfort associated with cystitis.
{R-39-41}
EL
CAN
Fever (treatment)
EL

Cattle, dogs, pigs,
 and 
EL
US
cats
EL
: Aspirin is 
used to reduce fever; however, the tr
eatment of fever with antipyretic 
medications is controversial and 
specific therapy for the underlying 
disease should be sought.
{R-39; 41}
Acceptance not established
Potentially effective
Inflammation (treatment);
Pain (treatment); or
EL
CAN
Fever (treatment)
EL

Horses:
 Due to the rapi
d elimination of 
salicylate by horses, it is ques
tionable whether therapeutic yet 
nontoxic concentrations can be maintained in the horse using 
conventional dosage intervals.  
EL
US,CAN
Cardiomyopathy (treatment adjunct)
EL

Cats:
 Thromboembolism 

 Aspirin
aspirin دواء
aspirin mechanism of action
aspirin protect 100
aspirin side effects
aspirin uses
aspirin dose
aspirin structure
aspirin indication

: Aspirin is 
used to reduce fever; however, the tr
eatment of fever with antipyretic 
medications is controversial and 
specific therapy for the underlying 
disease should be sought.
{R-39; 41}
Acceptance not established
Potentially effective
Inflammation (treatment);
Pain (treatment); or
EL
CAN
Fever (treatment)
EL

Horses:
 Due to the rapi
d elimination of 
salicylate by horses, it is ques
tionable whether therapeutic yet 
nontoxic concentrations can be maintained in the horse using 
conventional dosage intervals.  
EL
US,CAN
Cardiomyopathy (treatment adjunct)
EL

Cats:
 Thromboembolism 

Regulatory Considerations
U.S.—
Aspirin does not have specific approval by the Food and Drug
Administration for use in animals; therefore, there are no
established withdrawal times for use of this medication in foodproducing
animals.{R-13} See recommendations on withdrawals for
extra-label administration in the Dosage Forms section of this
monograph.
Chemistry
Source: Manufactured from salicylic acid and acetic anhydride.{R-14}
Chemical name: Benzoic acid, 2-(acetyloxy)-.{R-15}
Molecular formula: C9H8O4.{R-15}
Molecular weight: 180.16.{R-15}
Description: Aspirin USP—White crystals, commonly tabular or needlelike,
or white, crystalline powder. Is odorless or has a faint odor. Is
stable in dry air; in moist air it gradually hydrolyzes to salicylic and
acetic acids.{R-16}
pKa: 3.5.{R-14; 17}
Solubility: Aspirin USP—Slightly soluble in water; freely soluble in
alcohol; soluble in chloroform and in ether; sparingly soluble in
absolute ether.{R-16}
Pharmacology/Pharmacokinetics
Note: See also Table 1. Pharmacology/Pharmacokinetics at the end of
this monograph.
Mechanism of action/Effect: The effectiveness of aspirin is largely due
Draft copy for review purposes only. Private property of USPC, Inc. Not for public disclosure. All rights reserved 3
to its ability to inhibit prostaglandin synthesis. This is done by
irreversibly blocking cyclooxygenase (prostaglandin synthase),
which catalyzes the conversion of arachidonic acid to endoperoxide
compounds; at appropriate doses, the drug decreases the formation
of both the prostaglandins and thromboxane A2 but not the
leukotrienes.{R-18}
Other actions/effects: It has been proposed that the gastrointestinal
toxicity of salicylates, especially aspirin, may be caused primarily
by reduction of the activity of prostaglandins (which exert a
protective effect on the gastrointestinal mucosa) because upper
gastrointestinal toxicity has been reported following rectal or
parenteral administration of a nonsteroidal anti-inflammatory drug.
However, when administered orally, these acidic medications
(unless administered in an enteric-coated formulation) probably also
exert a direct irritant or erosive effect on the mucosa.{R-19}
Absorption: Salicylates are rapidly and completely absorbed following
oral administration to cats, dogs, and pigs. They are slowly and
incompletely absorbed by ruminants and horses.
Distribution: Free aspirin is widely distributed into various tissues of the
body.
Biotransformation: Aspirin is rapidly hydrolyzed to salicylic acid by
plasma esterases in all species.{R-20}
Time to peak plasma concentration: Human data—Generally 1 to 2
hours with single doses; may be more rapid with liquid dosage forms;
may be delayed with delayed-release tablet or capsule formulations.{R-
19}
Peak plasma concentration: Therapeutic serum salicylate
concentrations varied from 9.15 to 11.90 mg/dL in dogs given plain
aspirin orally at a dose of 25 mg per kg of body weight (mg/kg) every
8 hours.{R-21}
Milk concentrations: Human data—Peak salicylate concentrations of
173 to 483 mcg/mL were measured in breast milk 5 to 8 hours after
maternal ingestion of a single total aspirin dose of 650 mg.{R-19}
Elimination: Renal, primarily as free salicylic acid and as conjugated
metabolites. In the horse, salicylic acid is the primary salicyl
compound found in urine while in other domesticated species varying
quantities of metabolites are excreted.
Cats: Aspirin has been shown to have dose-dependent elimination in
cats, with longer elimination half-lives seen with larger doses.
Precautions to Consider
Species sensitivity
Cats—Cats may develop salicylism unless aspirin dosage is carefully
controlled. Cats are deficient in the enzyme glucuronyl transferase, an
important conjugation mechanism in other species.
Dogs—Some individual dogs will not tolerate continuous therapy with
aspirin because they develop gastrointestinal irritation.
Lactation
Salicylates are distributed into milk; however, problems have not been
observed in nursing offspring.
Pediatrics
Salicylates are more slowly eliminated in animals less than 30 days of
age. In addition, the extent of protein binding is less during this
period.
Human precautions to consider{R-19}
In addition to the above precautions for the use of this medication in
animals, the



نوع الكتاب : pdf.
اذا اعجبك الكتاب فضلاً اضغط على أعجبني
و يمكنك تحميله من هنا:

تحميل  Aspirin



كتب اخرى في كتب الطب

القانون في الطب PDF

قراءة و تحميل كتاب القانون في الطب PDF مجانا

المعتمد في الأدوية المفردة (ط. العلمية) PDF

قراءة و تحميل كتاب المعتمد في الأدوية المفردة (ط. العلمية) PDF مجانا

من مؤلفات ابن سينا الطبية PDF

قراءة و تحميل كتاب من مؤلفات ابن سينا الطبية PDF مجانا

آلآم أسفل الظهر PDF

قراءة و تحميل كتاب آلآم أسفل الظهر PDF مجانا

2. Treatment of potassium balance disorders PDF

قراءة و تحميل كتاب 2. Treatment of potassium balance disorders PDF مجانا

أرجوزة بن عبد ربه ف الطب PDF

قراءة و تحميل كتاب أرجوزة بن عبد ربه ف الطب PDF مجانا

دليل الآباء والأمهات للتعامل مع الشلل الدماغي PDF

قراءة و تحميل كتاب دليل الآباء والأمهات للتعامل مع الشلل الدماغي PDF مجانا

موسوعة أمراض العظام والكسور والعمود الفقرى PDF

قراءة و تحميل كتاب موسوعة أمراض العظام والكسور والعمود الفقرى PDF مجانا

المزيد من كتب الطب في مكتبة كتب الطب , المزيد من كتب صيدلة في مكتبة كتب صيدلة , المزيد من الطب البشرى العام في مكتبة الطب البشرى العام , المزيد من كتب طب بيطرى في مكتبة كتب طب بيطرى , المزيد من كتب طب اسنان في مكتبة كتب طب اسنان , المزيد من كتب تمريض في مكتبة كتب تمريض , المزيد من الطب التكميلي - الطب البديل في مكتبة الطب التكميلي - الطب البديل , المزيد من كتب علاج طبيعى في مكتبة كتب علاج طبيعى
عرض كل كتب الطب ..
اقرأ المزيد في مكتبة كتب تقنية , اقرأ المزيد في مكتبة كتب إسلامية , اقرأ المزيد في مكتبة كتب الهندسة و التكنولوجيا , اقرأ المزيد في مكتبة كتب التنمية البشرية , اقرأ المزيد في مكتبة الكتب التعليمية , اقرأ المزيد في مكتبة القصص و الروايات و المجلات , اقرأ المزيد في مكتبة كتب التاريخ , اقرأ المزيد في مكتبة كتب الأطفال قصص و مجلات , اقرأ المزيد في مكتبة كتب تعلم اللغات , اقرأ المزيد في مكتبة الكتب و الموسوعات العامة , اقرأ المزيد في مكتبة كتب الطب , اقرأ المزيد في مكتبة كتب الأدب , اقرأ المزيد في مكتبة كتب الروايات الأجنبية والعالمية , اقرأ المزيد في مكتبة كتب علوم سياسية و قانونية , اقرأ المزيد في مكتبة كتب اللياقة البدنية والصحة العامة , اقرأ المزيد في مكتبة الكتب الغير مصنّفة , اقرأ المزيد في مكتبة كتب الطبخ و الديكور , اقرأ المزيد في مكتبة كتب المعاجم و اللغات , اقرأ المزيد في مكتبة كتب علوم عسكرية و قانون دولي
جميع مكتبات الكتب ..